Laurent David

DAVID_LaurentFull Professor
LIFE
Membership : Université Claude Bernard Lyon 1
Location : UCBL

natural polymers / glass transition / radiation scattering / relaxation phenomena / gels / tissue engineering

Research themes/centers of interest

Natural polymers, polysaccharides, chitosan, chitin
hydrogels, physico-chemical properties of polysaccharides
Polyelectrolyte complexation
Spinning of natural polymers (polysaccharides)
chelating derivatives of chitosan

In vitro/ ex vivo/ in vivo tissue engineering
Repair of damaged spinal cords
Fertility preservation
Radiation protection
Biomimetics (insect cuticle models)

Major publications

  • Ladet, S.; David, L.; Domard, D.; Multimembrane hydrogels, Nature 2008, 452, 76-80, doi: 10.1038/nature06619
  • Passieux R, Sudre G, Montembault A, e Renard M, Hagège A, Alcouffe P, Haddane A, Vandesteene M, Boucard N, Bordenave L, and David L Cytocompatibility / Antibacterial Activity Trade-off for Knittable Wet-Spun Chitosan Monofilaments Functionalized by the In Situ Incorporation of Cu2+ and Zn2+ ACS Biomaterials Science & Engineering 2022 8 (4), 1735-1748 doi 10.1021/acsbiomaterials.2c00079
  • Chedly J, Soares S, Montembault A, von Boxberg Y, Veron-Ravaille M, Mouffle C, Benassy M-N, Taxi J, David L, Nothias F, Physical chitosan microhydrogels as scaffolds for spinal cord injury restoration and axon regeneration, Biomaterials, 2017, 138, 91-107, doi:10.1016/j.biomaterials.2017.05.024
  • Sereni N, Enache A., Sudre G, Montembault A., Rochas C., Durand P., Perrard M-H, Bozga G., Puaux J.P., Delair T, David L. Dynamic Structuration of Physical Chitosan Hydrogels, Langmuir, 2017 33(44) 12697-12707 doi: 10.1021/acs.langmuir.7b02997
  • Howard JA, Kuznietsova H, Dziubenko N, Aigle A, Natuzzi M, Thomas E, Lysenko V, David L, Brichart T, Lux F, Tillement O. Combating lead and cadmium exposure with an orally administered chitosan-based chelating polymer. Sci Rep. 2023 Feb 7;13(1):2215. doi: 10.1038/s41598-023-28968-4.